Does OLAPARIB Cause Intestinal perforation? 16 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 16 reports of Intestinal perforation have been filed in association with OLAPARIB (Lynparza). This represents 0.1% of all adverse event reports for OLAPARIB.
16
Reports of Intestinal perforation with OLAPARIB
0.1%
of all OLAPARIB reports
6
Deaths
6
Hospitalizations
How Dangerous Is Intestinal perforation From OLAPARIB?
Of the 16 reports, 6 (37.5%) resulted in death, 6 (37.5%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OLAPARIB. However, 16 reports have been filed with the FAERS database.
What Other Side Effects Does OLAPARIB Cause?
Death (4,378)
Malignant neoplasm progression (1,862)
Nausea (1,582)
Anaemia (1,455)
Fatigue (1,437)
Off label use (777)
Vomiting (642)
Drug ineffective (563)
Diarrhoea (514)
Asthenia (491)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which OLAPARIB Alternatives Have Lower Intestinal perforation Risk?
OLAPARIB vs OLARATUMAB
OLAPARIB vs OLECLUMAB
OLAPARIB vs OLIVE OIL\SOYBEAN OIL
OLAPARIB vs OLMESARTAN
OLAPARIB vs OLMESARTAN MEDOXOMIL