Does OXALIPLATIN Cause Leukoencephalopathy? 66 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Leukoencephalopathy have been filed in association with OXALIPLATIN (Oxaliplatin). This represents 0.1% of all adverse event reports for OXALIPLATIN.
66
Reports of Leukoencephalopathy with OXALIPLATIN
0.1%
of all OXALIPLATIN reports
18
Deaths
37
Hospitalizations
How Dangerous Is Leukoencephalopathy From OXALIPLATIN?
Of the 66 reports, 18 (27.3%) resulted in death, 37 (56.1%) required hospitalization, and 5 (7.6%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for OXALIPLATIN.
What Other Side Effects Does OXALIPLATIN Cause?
Diarrhoea (4,963)
Nausea (4,250)
Neuropathy peripheral (3,662)
Off label use (3,603)
Neutropenia (3,391)
Vomiting (3,383)
Disease progression (3,370)
Thrombocytopenia (2,886)
Dyspnoea (2,779)
Pyrexia (2,269)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which OXALIPLATIN Alternatives Have Lower Leukoencephalopathy Risk?
OXALIPLATIN vs OXAPROZIN
OXALIPLATIN vs OXAZEPAM
OXALIPLATIN vs OXCARBAZEPINE
OXALIPLATIN vs OXITRIPTAN
OXALIPLATIN vs OXOMEMAZINE