Does PACLITAXEL Cause Hyperammonaemia? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hyperammonaemia have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.0% of all adverse event reports for PACLITAXEL.
14
Reports of Hyperammonaemia with PACLITAXEL
0.0%
of all PACLITAXEL reports
2
Deaths
11
Hospitalizations
How Dangerous Is Hyperammonaemia From PACLITAXEL?
Of the 14 reports, 2 (14.3%) resulted in death, 11 (78.6%) required hospitalization, and 3 (21.4%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PACLITAXEL. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which PACLITAXEL Alternatives Have Lower Hyperammonaemia Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON