Does PACLITAXEL Cause Leukoencephalopathy? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Leukoencephalopathy have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 0.0% of all adverse event reports for PACLITAXEL.
15
Reports of Leukoencephalopathy with PACLITAXEL
0.0%
of all PACLITAXEL reports
3
Deaths
5
Hospitalizations
How Dangerous Is Leukoencephalopathy From PACLITAXEL?
Of the 15 reports, 3 (20.0%) resulted in death, 5 (33.3%) required hospitalization, and 2 (13.3%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for PACLITAXEL.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which PACLITAXEL Alternatives Have Lower Leukoencephalopathy Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON