Does PANITUMUMAB Cause Hyperammonaemia? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hyperammonaemia have been filed in association with PANITUMUMAB (Vectibix). This represents 0.2% of all adverse event reports for PANITUMUMAB.
19
Reports of Hyperammonaemia with PANITUMUMAB
0.2%
of all PANITUMUMAB reports
0
Deaths
12
Hospitalizations
How Dangerous Is Hyperammonaemia From PANITUMUMAB?
Of the 19 reports, 12 (63.2%) required hospitalization, and 3 (15.8%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PANITUMUMAB. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does PANITUMUMAB Cause?
Rash (1,392)
Diarrhoea (1,123)
Death (767)
Dermatitis acneiform (758)
Neutropenia (757)
Skin toxicity (728)
Neuropathy peripheral (613)
Hypomagnesaemia (611)
Nausea (608)
Disease progression (600)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which PANITUMUMAB Alternatives Have Lower Hyperammonaemia Risk?
PANITUMUMAB vs PANOBINOSTAT
PANITUMUMAB vs PANTOPRAZOLE
PANITUMUMAB vs PANTOPRAZOLE ANHYDROUS
PANITUMUMAB vs PANTOTHENIC ACID
PANITUMUMAB vs PAPAVERINE