Does PANITUMUMAB Cause Intestinal perforation? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Intestinal perforation have been filed in association with PANITUMUMAB (Vectibix). This represents 0.2% of all adverse event reports for PANITUMUMAB.
24
Reports of Intestinal perforation with PANITUMUMAB
0.2%
of all PANITUMUMAB reports
8
Deaths
10
Hospitalizations
How Dangerous Is Intestinal perforation From PANITUMUMAB?
Of the 24 reports, 8 (33.3%) resulted in death, 10 (41.7%) required hospitalization, and 5 (20.8%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PANITUMUMAB. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does PANITUMUMAB Cause?
Rash (1,392)
Diarrhoea (1,123)
Death (767)
Dermatitis acneiform (758)
Neutropenia (757)
Skin toxicity (728)
Neuropathy peripheral (613)
Hypomagnesaemia (611)
Nausea (608)
Disease progression (600)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which PANITUMUMAB Alternatives Have Lower Intestinal perforation Risk?
PANITUMUMAB vs PANOBINOSTAT
PANITUMUMAB vs PANTOPRAZOLE
PANITUMUMAB vs PANTOPRAZOLE ANHYDROUS
PANITUMUMAB vs PANTOTHENIC ACID
PANITUMUMAB vs PAPAVERINE