Does PEMBROLIZUMAB Cause Neurotoxicity? 110 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 110 reports of Neurotoxicity have been filed in association with PEMBROLIZUMAB (KEYTRUDA). This represents 0.1% of all adverse event reports for PEMBROLIZUMAB.
110
Reports of Neurotoxicity with PEMBROLIZUMAB
0.1%
of all PEMBROLIZUMAB reports
5
Deaths
15
Hospitalizations
How Dangerous Is Neurotoxicity From PEMBROLIZUMAB?
Of the 110 reports, 5 (4.5%) resulted in death, 15 (13.6%) required hospitalization, and 5 (4.5%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEMBROLIZUMAB. However, 110 reports have been filed with the FAERS database.
What Other Side Effects Does PEMBROLIZUMAB Cause?
Malignant neoplasm progression (10,111)
Death (4,744)
Diarrhoea (4,251)
Fatigue (3,833)
Off label use (3,416)
Product use in unapproved indication (3,191)
Pyrexia (3,155)
Rash (2,900)
Nausea (2,670)
Decreased appetite (2,486)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which PEMBROLIZUMAB Alternatives Have Lower Neurotoxicity Risk?
PEMBROLIZUMAB vs PEMETREXED
PEMBROLIZUMAB vs PEMIGATINIB
PEMBROLIZUMAB vs PENICILLAMINE
PEMBROLIZUMAB vs PENICILLIN
PEMBROLIZUMAB vs PENICILLIN G