Does PERTUZUMAB Cause Intestinal perforation? 24 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 24 reports of Intestinal perforation have been filed in association with PERTUZUMAB (PERJETA). This represents 0.1% of all adverse event reports for PERTUZUMAB.
24
Reports of Intestinal perforation with PERTUZUMAB
0.1%
of all PERTUZUMAB reports
10
Deaths
10
Hospitalizations
How Dangerous Is Intestinal perforation From PERTUZUMAB?
Of the 24 reports, 10 (41.7%) resulted in death, 10 (41.7%) required hospitalization, and 1 (4.2%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PERTUZUMAB. However, 24 reports have been filed with the FAERS database.
What Other Side Effects Does PERTUZUMAB Cause?
Diarrhoea (3,343)
Off label use (1,886)
Fatigue (1,672)
Nausea (1,669)
Myelosuppression (1,311)
Disease progression (1,142)
Vomiting (1,096)
Dyspnoea (987)
Neuropathy peripheral (983)
Pyrexia (926)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which PERTUZUMAB Alternatives Have Lower Intestinal perforation Risk?
PERTUZUMAB vs PERTUZUMAB\TRASTUZUMAB
PERTUZUMAB vs PETROLATUM
PERTUZUMAB vs PEVONEDISTAT
PERTUZUMAB vs PEXIDARTINIB
PERTUZUMAB vs PHENACETIN