Does PHENYTOIN Cause Neurotoxicity? 66 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 66 reports of Neurotoxicity have been filed in association with PHENYTOIN (PHENYTOIN SODIUM). This represents 0.5% of all adverse event reports for PHENYTOIN.
66
Reports of Neurotoxicity with PHENYTOIN
0.5%
of all PHENYTOIN reports
0
Deaths
17
Hospitalizations
How Dangerous Is Neurotoxicity From PHENYTOIN?
Of the 66 reports, 17 (25.8%) required hospitalization, and 14 (21.2%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PHENYTOIN. However, 66 reports have been filed with the FAERS database.
What Other Side Effects Does PHENYTOIN Cause?
Drug ineffective (2,753)
Seizure (1,907)
Toxicity to various agents (1,248)
Drug hypersensitivity (898)
Off label use (852)
Drug interaction (772)
Drug reaction with eosinophilia and systemic symptoms (673)
Status epilepticus (544)
Fall (436)
Rash (414)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which PHENYTOIN Alternatives Have Lower Neurotoxicity Risk?
PHENYTOIN vs PHLEUM PRATENSE POLLEN
PHENYTOIN vs PHLOROGLUCINOL
PHENYTOIN vs PHLOROGLUCINOL\1,3,5-TRIMETHOXYBENZENE
PHENYTOIN vs PHOLCODINE
PHENYTOIN vs PHOSPHORUS