Does POLYMYXIN B Cause Neurotoxicity? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Neurotoxicity have been filed in association with POLYMYXIN B (polymyxin b sulfate and trimethoprim sulfate). This represents 2.3% of all adverse event reports for POLYMYXIN B.
15
Reports of Neurotoxicity with POLYMYXIN B
2.3%
of all POLYMYXIN B reports
1
Deaths
5
Hospitalizations
How Dangerous Is Neurotoxicity From POLYMYXIN B?
Of the 15 reports, 1 (6.7%) resulted in death, 5 (33.3%) required hospitalization, and 3 (20.0%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for POLYMYXIN B. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does POLYMYXIN B Cause?
Drug ineffective (260)
Macular degeneration (168)
Off label use (85)
Pain (66)
Drug hypersensitivity (62)
Nausea (62)
Acute kidney injury (53)
Pyrexia (43)
Malaise (42)
Paraesthesia oral (42)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which POLYMYXIN B Alternatives Have Lower Neurotoxicity Risk?
POLYMYXIN B vs POLYMYXIN B\TRIMETHOPRIM
POLYMYXIN B vs POLYVINYL ALCOHOL\POVIDONE
POLYMYXIN B vs POMALIDOMIDE
POLYMYXIN B vs POMALYST
POLYMYXIN B vs PONATINIB