Does PONATINIB Cause Leukoencephalopathy? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Leukoencephalopathy have been filed in association with PONATINIB (Iclusig). This represents 0.1% of all adverse event reports for PONATINIB.
5
Reports of Leukoencephalopathy with PONATINIB
0.1%
of all PONATINIB reports
2
Deaths
2
Hospitalizations
How Dangerous Is Leukoencephalopathy From PONATINIB?
Of the 5 reports, 2 (40.0%) resulted in death, 2 (40.0%) required hospitalization.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for PONATINIB.
What Other Side Effects Does PONATINIB Cause?
Death (1,735)
Off label use (1,071)
Product dose omission issue (817)
Fatigue (687)
Rash (639)
Headache (553)
Pyrexia (542)
Nausea (466)
Hospitalisation (459)
Constipation (435)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which PONATINIB Alternatives Have Lower Leukoencephalopathy Risk?
PONATINIB vs PONATINIB\PONATINIB
PONATINIB vs PONESIMOD
PONATINIB vs PORACTANT ALFA
PONATINIB vs PORFIMER
PONATINIB vs POSACONAZOLE