Does PROCARBAZINE Cause Neurotoxicity? 30 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 30 reports of Neurotoxicity have been filed in association with PROCARBAZINE (Matulane). This represents 0.5% of all adverse event reports for PROCARBAZINE.
30
Reports of Neurotoxicity with PROCARBAZINE
0.5%
of all PROCARBAZINE reports
20
Deaths
2
Hospitalizations
How Dangerous Is Neurotoxicity From PROCARBAZINE?
Of the 30 reports, 20 (66.7%) resulted in death, 2 (6.7%) required hospitalization, and 1 (3.3%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROCARBAZINE. However, 30 reports have been filed with the FAERS database.
What Other Side Effects Does PROCARBAZINE Cause?
Nausea (1,029)
Fatigue (890)
Vomiting (375)
Neutropenia (311)
Off label use (301)
Constipation (274)
Platelet count decreased (246)
White blood cell count decreased (229)
Headache (222)
Acute myeloid leukaemia (195)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which PROCARBAZINE Alternatives Have Lower Neurotoxicity Risk?
PROCARBAZINE vs PROCHLORPERAZINE
PROCARBAZINE vs PROCHLORPERAZINE EDISYLATE
PROCARBAZINE vs PROCRIT
PROCARBAZINE vs PROCYCLIDINE
PROCARBAZINE vs PROGESTERONE