Does PROPOFOL Cause Hyperammonaemia? 19 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 19 reports of Hyperammonaemia have been filed in association with PROPOFOL (Propofol). This represents 0.1% of all adverse event reports for PROPOFOL.
19
Reports of Hyperammonaemia with PROPOFOL
0.1%
of all PROPOFOL reports
3
Deaths
11
Hospitalizations
How Dangerous Is Hyperammonaemia From PROPOFOL?
Of the 19 reports, 3 (15.8%) resulted in death, 11 (57.9%) required hospitalization, and 5 (26.3%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PROPOFOL. However, 19 reports have been filed with the FAERS database.
What Other Side Effects Does PROPOFOL Cause?
Drug ineffective (1,627)
Anaphylactic shock (1,494)
Hypotension (1,388)
Off label use (889)
Anaphylactic reaction (862)
Cardiac arrest (758)
Bradycardia (470)
Tachycardia (464)
Propofol infusion syndrome (420)
Foetal exposure during pregnancy (389)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which PROPOFOL Alternatives Have Lower Hyperammonaemia Risk?
PROPOFOL vs PROPOXYPHENE
PROPOFOL vs PROPOXYPHENE/ACETAMINOPHEN
PROPOFOL vs PROPRANOLOL
PROPOFOL vs PROPRANOLOL\PROPRANOLOL
PROPOFOL vs PROPYLENE GLYCOL