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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does REGORAFENIB Cause Intestinal perforation? 18 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 18 reports of Intestinal perforation have been filed in association with REGORAFENIB (Stivarga). This represents 0.2% of all adverse event reports for REGORAFENIB.

18
Reports of Intestinal perforation with REGORAFENIB
0.2%
of all REGORAFENIB reports
4
Deaths
12
Hospitalizations

How Dangerous Is Intestinal perforation From REGORAFENIB?

Of the 18 reports, 4 (22.2%) resulted in death, 12 (66.7%) required hospitalization, and 1 (5.6%) were considered life-threatening.

Is Intestinal perforation Listed in the Official Label?

Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for REGORAFENIB.

What Other Side Effects Does REGORAFENIB Cause?

Off label use (1,906) Fatigue (1,530) Palmar-plantar erythrodysaesthesia syndrome (1,230) Diarrhoea (1,221) Decreased appetite (941) Asthenia (825) Death (813) Dysphonia (702) Nausea (688) Pain in extremity (686)

What Other Drugs Cause Intestinal perforation?

ADALIMUMAB (1,010) BEVACIZUMAB (600) RITUXIMAB (321) TOCILIZUMAB (276) PREDNISONE (266) CYCLOPHOSPHAMIDE (262) DOXORUBICIN (240) LENVATINIB (228) INFLIXIMAB (226) PEMBROLIZUMAB (220)

Which REGORAFENIB Alternatives Have Lower Intestinal perforation Risk?

REGORAFENIB vs REGORAFENIB\REGORAFENIB REGORAFENIB vs RELATLIMAB REGORAFENIB vs RELPAX REGORAFENIB vs RELUGOLIX REGORAFENIB vs REMDESIVIR

Related Pages

REGORAFENIB Full Profile All Intestinal perforation Reports All Drugs Causing Intestinal perforation REGORAFENIB Demographics