Does RIFAMPIN Cause Hyperammonaemia? 28 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 28 reports of Hyperammonaemia have been filed in association with RIFAMPIN (Rifampin). This represents 0.2% of all adverse event reports for RIFAMPIN.
28
Reports of Hyperammonaemia with RIFAMPIN
0.2%
of all RIFAMPIN reports
26
Deaths
28
Hospitalizations
How Dangerous Is Hyperammonaemia From RIFAMPIN?
Of the 28 reports, 26 (92.9%) resulted in death, 28 (100.0%) required hospitalization, and 2 (7.1%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIFAMPIN. However, 28 reports have been filed with the FAERS database.
What Other Side Effects Does RIFAMPIN Cause?
Drug ineffective (1,238)
Drug reaction with eosinophilia and systemic symptoms (1,049)
Drug interaction (735)
Pyrexia (735)
Acute kidney injury (684)
Drug-induced liver injury (684)
Off label use (640)
Condition aggravated (597)
Nausea (572)
Paradoxical drug reaction (570)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which RIFAMPIN Alternatives Have Lower Hyperammonaemia Risk?
RIFAMPIN vs RIFAMYCIN
RIFAMPIN vs RIFAPENTINE
RIFAMPIN vs RIFAXIMIN
RIFAMPIN vs RILMENIDINE
RIFAMPIN vs RILONACEPT