Does RIFAXIMIN Cause Hyperammonaemia? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Hyperammonaemia have been filed in association with RIFAXIMIN (XIFAXAN). This represents 0.1% of all adverse event reports for RIFAXIMIN.
20
Reports of Hyperammonaemia with RIFAXIMIN
0.1%
of all RIFAXIMIN reports
6
Deaths
14
Hospitalizations
How Dangerous Is Hyperammonaemia From RIFAXIMIN?
Of the 20 reports, 6 (30.0%) resulted in death, 14 (70.0%) required hospitalization, and 3 (15.0%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for RIFAXIMIN. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does RIFAXIMIN Cause?
Death (3,687)
Hospitalisation (1,605)
Therapy interrupted (875)
Off label use (802)
Diarrhoea (709)
Ammonia increased (676)
Inability to afford medication (672)
Insurance issue (577)
Confusional state (530)
Hepatic cirrhosis (480)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which RIFAXIMIN Alternatives Have Lower Hyperammonaemia Risk?
RIFAXIMIN vs RILMENIDINE
RIFAXIMIN vs RILONACEPT
RIFAXIMIN vs RILPIVIRINE
RIFAXIMIN vs RILUZOLE
RIFAXIMIN vs RIMABOTULINUMTOXINB