Does SORAFENIB Cause Intestinal perforation? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Intestinal perforation have been filed in association with SORAFENIB (sorafenib). This represents 0.1% of all adverse event reports for SORAFENIB.
13
Reports of Intestinal perforation with SORAFENIB
0.1%
of all SORAFENIB reports
2
Deaths
7
Hospitalizations
How Dangerous Is Intestinal perforation From SORAFENIB?
Of the 13 reports, 2 (15.4%) resulted in death, 7 (53.8%) required hospitalization, and 1 (7.7%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which SORAFENIB Alternatives Have Lower Intestinal perforation Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK