Does SORAFENIB Cause Leukoencephalopathy? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Leukoencephalopathy have been filed in association with SORAFENIB (sorafenib). This represents 0.1% of all adverse event reports for SORAFENIB.
5
Reports of Leukoencephalopathy with SORAFENIB
0.1%
of all SORAFENIB reports
2
Deaths
2
Hospitalizations
How Dangerous Is Leukoencephalopathy From SORAFENIB?
Of the 5 reports, 2 (40.0%) resulted in death, 2 (40.0%) required hospitalization.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for SORAFENIB.
What Other Side Effects Does SORAFENIB Cause?
Hepatocellular carcinoma (1,665)
Diarrhoea (1,611)
Off label use (1,587)
Fatigue (1,041)
Palmar-plantar erythrodysaesthesia syndrome (1,040)
Decreased appetite (906)
Death (904)
Asthenia (777)
Nausea (716)
Rash (613)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which SORAFENIB Alternatives Have Lower Leukoencephalopathy Risk?
SORAFENIB vs SORGHUM HALEPENSE POLLEN
SORAFENIB vs SOTAGLIFLOZIN
SORAFENIB vs SOTALOL
SORAFENIB vs SOTATERCEPT
SORAFENIB vs SOTATERCEPT-CSRK