Does THALIDOMIDE Cause Intestinal perforation? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Intestinal perforation have been filed in association with THALIDOMIDE (Thalomid). This represents 0.1% of all adverse event reports for THALIDOMIDE.
22
Reports of Intestinal perforation with THALIDOMIDE
0.1%
of all THALIDOMIDE reports
4
Deaths
17
Hospitalizations
How Dangerous Is Intestinal perforation From THALIDOMIDE?
Of the 22 reports, 4 (18.2%) resulted in death, 17 (77.3%) required hospitalization, and 7 (31.8%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for THALIDOMIDE.
What Other Side Effects Does THALIDOMIDE Cause?
Plasma cell myeloma (1,652)
Off label use (1,356)
Death (1,161)
Neuropathy peripheral (1,068)
Drug ineffective (789)
Pneumonia (694)
Fatigue (643)
Constipation (461)
Thrombocytopenia (429)
Neutropenia (420)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which THALIDOMIDE Alternatives Have Lower Intestinal perforation Risk?
THALIDOMIDE vs THALOMID
THALIDOMIDE vs THEOPHYLLINE
THALIDOMIDE vs THEOPHYLLINE ANHYDROUS
THALIDOMIDE vs THIAMINE
THALIDOMIDE vs THIOCOLCHICOSIDE