Does THIOTEPA Cause Neurotoxicity? 76 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 76 reports of Neurotoxicity have been filed in association with THIOTEPA (Thiotepa). This represents 1.1% of all adverse event reports for THIOTEPA.
76
Reports of Neurotoxicity with THIOTEPA
1.1%
of all THIOTEPA reports
30
Deaths
4
Hospitalizations
How Dangerous Is Neurotoxicity From THIOTEPA?
Of the 76 reports, 30 (39.5%) resulted in death, 4 (5.3%) required hospitalization, and 1 (1.3%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
Yes, Neurotoxicity is listed as a known adverse reaction in the official FDA drug label for THIOTEPA.
What Other Side Effects Does THIOTEPA Cause?
Off label use (762)
Febrile neutropenia (645)
Mucosal inflammation (616)
Cytomegalovirus infection (446)
Product use in unapproved indication (425)
Pyrexia (359)
Drug ineffective (358)
Acute graft versus host disease in skin (355)
Acute graft versus host disease (331)
Cytomegalovirus infection reactivation (325)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which THIOTEPA Alternatives Have Lower Neurotoxicity Risk?
THIOTEPA vs THIOTHIXENE
THIOTEPA vs THROMBIN
THIOTEPA vs THROMBIN HUMAN
THIOTEPA vs THYMOCYTE IMMUNE GLOBULIN NOS
THIOTEPA vs THYMOGLOBULINE