Does TRAMETINIB DIMETHYL SULFOXIDE Cause Intestinal perforation? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Intestinal perforation have been filed in association with TRAMETINIB DIMETHYL SULFOXIDE (Mekinist). This represents 0.1% of all adverse event reports for TRAMETINIB DIMETHYL SULFOXIDE.
22
Reports of Intestinal perforation with TRAMETINIB DIMETHYL SULFOXIDE
0.1%
of all TRAMETINIB DIMETHYL SULFOXIDE reports
5
Deaths
9
Hospitalizations
How Dangerous Is Intestinal perforation From TRAMETINIB DIMETHYL SULFOXIDE?
Of the 22 reports, 5 (22.7%) resulted in death, 9 (40.9%) required hospitalization, and 2 (9.1%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for TRAMETINIB DIMETHYL SULFOXIDE.
What Other Side Effects Does TRAMETINIB DIMETHYL SULFOXIDE Cause?
Death (2,998)
Pyrexia (2,660)
Rash (1,271)
Fatigue (1,143)
Malignant neoplasm progression (1,114)
Nausea (1,085)
Chills (965)
Diarrhoea (867)
Vomiting (720)
Product use in unapproved indication (687)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which TRAMETINIB DIMETHYL SULFOXIDE Alternatives Have Lower Intestinal perforation Risk?
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANDOLAPRIL\VERAPAMIL
TRAMETINIB DIMETHYL SULFOXIDE vs TRANEXAMIC ACID
TRAMETINIB DIMETHYL SULFOXIDE vs TRANYLCYPROMINE
TRAMETINIB DIMETHYL SULFOXIDE vs TRASTUZUMAB