Does TRASTUZUMAB Cause Neurotoxicity? 280 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 280 reports of Neurotoxicity have been filed in association with TRASTUZUMAB (Trazimera). This represents 0.6% of all adverse event reports for TRASTUZUMAB.
280
Reports of Neurotoxicity with TRASTUZUMAB
0.6%
of all TRASTUZUMAB reports
16
Deaths
39
Hospitalizations
How Dangerous Is Neurotoxicity From TRASTUZUMAB?
Of the 280 reports, 16 (5.7%) resulted in death, 39 (13.9%) required hospitalization, and 2 (0.7%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for TRASTUZUMAB. However, 280 reports have been filed with the FAERS database.
What Other Side Effects Does TRASTUZUMAB Cause?
Diarrhoea (4,996)
Off label use (3,802)
Nausea (3,499)
Fatigue (3,417)
Myelosuppression (2,552)
Disease progression (2,449)
Death (2,378)
Vomiting (2,244)
Dyspnoea (2,010)
Pyrexia (1,886)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which TRASTUZUMAB Alternatives Have Lower Neurotoxicity Risk?
TRASTUZUMAB vs TRASTUZUMAB-ANNS
TRASTUZUMAB vs TRASTUZUMAB DERUXTECAN
TRASTUZUMAB vs TRASTUZUMAB-DKST
TRASTUZUMAB vs TRASTUZUMAB-DTTB
TRASTUZUMAB vs TRASTUZUMAB EMTANSINE