Does VINCRISTINE Cause Hyperammonaemia? 73 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 73 reports of Hyperammonaemia have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.1% of all adverse event reports for VINCRISTINE.
73
Reports of Hyperammonaemia with VINCRISTINE
0.1%
of all VINCRISTINE reports
32
Deaths
53
Hospitalizations
How Dangerous Is Hyperammonaemia From VINCRISTINE?
Of the 73 reports, 32 (43.8%) resulted in death, 53 (72.6%) required hospitalization, and 20 (27.4%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 73 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which VINCRISTINE Alternatives Have Lower Hyperammonaemia Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE