Adrenergic alpha2-Agonists [MoA]: Side Effects & Safety Data for 5 Drugs
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Adrenergic alpha2-Agonists [MoA] includes 5 drugs with a combined 27,548 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
5
Drugs in Class
27,548
Combined Reports
All Adrenergic alpha2-Agonists [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| CLONIDINE | Clonidine hydrochloride | 12,593 | 2,401 | 3,920 | 19.1% |
| TIZANIDINE | Tizanidne hydrochloride | 5,533 | 1,068 | 1,764 | 19.3% |
| GUANFACINE | Guanfacine | 3,538 | 122 | 821 | 3.4% |
| DEXMEDETOMIDINE | Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride | 3,280 | 235 | 1,258 | 7.2% |
| METHYLDOPA | Methyldopa | 2,604 | 73 | 728 | 2.8% |
Common Side Effects in Adrenergic alpha2-Agonists [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 3,319 | 249 |
| Off label use | 2,261 | 281 |
| Completed suicide | 1,664 | 1,657 |
| Somnolence | 1,625 | 14 |
| Toxicity to various agents | 1,499 | 784 |
| Hypotension | 1,496 | 105 |
| Hypertension | 1,478 | 339 |
| Fatigue | 1,475 | 262 |
| Headache | 1,383 | 272 |
| Pain | 1,376 | 251 |