Adrenergic alpha2-Agonists [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 3,319 | 5 | 249 | 918 | 199 |
| Off label use | 2,261 | 5 | 281 | 778 | 190 |
| Completed suicide | 1,664 | 4 | 1,657 | 555 | 37 |
| Somnolence | 1,625 | 5 | 14 | 784 | 128 |
| Toxicity to various agents | 1,499 | 5 | 784 | 866 | 176 |
| Hypotension | 1,496 | 5 | 105 | 924 | 251 |
| Hypertension | 1,478 | 5 | 339 | 620 | 150 |
| Fatigue | 1,475 | 5 | 262 | 335 | 75 |
| Headache | 1,383 | 5 | 272 | 264 | 82 |
| Pain | 1,376 | 5 | 251 | 269 | 56 |
| Foetal exposure during pregnancy | 1,217 | 5 | 62 | 213 | 48 |
| Bradycardia | 1,199 | 5 | 65 | 716 | 239 |
| Overdose | 1,065 | 5 | 197 | 507 | 163 |
| Dizziness | 1,064 | 5 | 172 | 354 | 88 |
| Exposure during pregnancy | 1,000 | 4 | 116 | 207 | 41 |
| Drug hypersensitivity | 993 | 5 | 132 | 74 | 31 |
| Nausea | 982 | 5 | 154 | 333 | 60 |
| Premature baby | 885 | 4 | 24 | 174 | 40 |
| Product use issue | 831 | 5 | 146 | 174 | 42 |
| Hypersensitivity | 825 | 4 | 245 | 60 | 33 |
| Maternal exposure during pregnancy | 810 | 4 | 44 | 318 | 65 |
| Hyperhidrosis | 767 | 4 | 113 | 111 | 19 |
| Condition aggravated | 738 | 5 | 163 | 297 | 109 |
| Pyrexia | 707 | 5 | 261 | 235 | 114 |
| Hepatic enzyme increased | 706 | 3 | 265 | 91 | 51 |
| Vomiting | 701 | 5 | 182 | 367 | 87 |
| Rash | 684 | 5 | 205 | 79 | 40 |
| Constipation | 680 | 4 | 114 | 91 | 19 |
| Insomnia | 673 | 5 | 47 | 199 | 51 |
| Dyspnoea | 670 | 5 | 131 | 282 | 78 |