Hedgehog Pathway Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Muscle spasms | 2,119 | 2 | 32 | 128 | 15 |
| Alopecia | 1,437 | 2 | 35 | 90 | 18 |
| Ageusia | 1,017 | 2 | 8 | 52 | 2 |
| Fatigue | 1,002 | 3 | 24 | 90 | 4 |
| Death | 846 | 3 | 818 | 32 | 4 |
| Dysgeusia | 758 | 3 | 26 | 43 | 11 |
| Nausea | 750 | 3 | 14 | 92 | 9 |
| Weight decreased | 746 | 2 | 22 | 68 | 9 |
| Decreased appetite | 728 | 3 | 24 | 96 | 12 |
| Diarrhoea | 514 | 3 | 26 | 64 | 8 |
| Off label use | 464 | 3 | 39 | 33 | 2 |
| Constipation | 379 | 3 | 4 | 39 | 4 |
| Asthenia | 341 | 3 | 20 | 73 | 9 |
| Arthralgia | 291 | 2 | 0 | 24 | 1 |
| Vomiting | 286 | 2 | 23 | 73 | 7 |
| Taste disorder | 265 | 2 | 4 | 20 | 0 |
| Pain | 262 | 2 | 16 | 51 | 9 |
| No adverse event | 247 | 1 | 1 | 0 | 0 |
| Myalgia | 242 | 2 | 1 | 24 | 2 |
| Drug ineffective | 237 | 3 | 17 | 18 | 5 |
| Headache | 199 | 3 | 6 | 28 | 3 |
| Malaise | 165 | 3 | 5 | 36 | 2 |
| Fall | 159 | 3 | 12 | 59 | 2 |
| Pneumonia | 155 | 3 | 36 | 102 | 11 |
| Dizziness | 145 | 2 | 5 | 31 | 1 |
| Basal cell carcinoma | 145 | 2 | 8 | 17 | 3 |
| Disease progression | 143 | 3 | 49 | 14 | 5 |
| Dehydration | 138 | 3 | 14 | 88 | 2 |
| Rash | 132 | 2 | 1 | 7 | 1 |
| Abdominal pain upper | 126 | 2 | 0 | 14 | 0 |