Local Anesthesia [PE] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 7,238 | 8 | 262 | 1,130 | 545 |
| Off label use | 3,611 | 6 | 273 | 782 | 303 |
| Product adhesion issue | 3,444 | 1 | 1 | 8 | 0 |
| Product quality issue | 3,284 | 5 | 9 | 41 | 10 |
| Drug ineffective for unapproved indication | 1,825 | 3 | 13 | 167 | 60 |
| Pain | 1,765 | 5 | 57 | 392 | 70 |
| Hypotension | 1,462 | 6 | 73 | 663 | 416 |
| Toxicity to various agents | 1,429 | 6 | 577 | 640 | 322 |
| Drug hypersensitivity | 1,401 | 7 | 80 | 170 | 108 |
| Dyspnoea | 1,301 | 6 | 119 | 487 | 221 |
| Vomiting | 1,133 | 5 | 169 | 373 | 138 |
| Nausea | 979 | 5 | 111 | 397 | 143 |
| Maternal exposure during pregnancy | 973 | 4 | 90 | 390 | 155 |
| Cardiac arrest | 935 | 4 | 313 | 449 | 493 |
| No adverse event | 883 | 3 | 3 | 20 | 2 |
| Product use in unapproved indication | 875 | 6 | 135 | 251 | 106 |
| Dizziness | 860 | 7 | 94 | 286 | 100 |
| Local anaesthetic systemic toxicity | 827 | 5 | 36 | 568 | 402 |
| Anaphylactic reaction | 789 | 5 | 26 | 278 | 260 |
| Hypoaesthesia | 785 | 5 | 90 | 266 | 82 |
| Exposure during pregnancy | 769 | 5 | 24 | 171 | 65 |
| Anaesthetic complication | 755 | 5 | 1 | 89 | 61 |
| Overdose | 702 | 6 | 151 | 378 | 188 |
| Anaphylactic shock | 699 | 4 | 63 | 216 | 411 |
| Bradycardia | 691 | 6 | 57 | 317 | 235 |
| Seizure | 659 | 5 | 95 | 299 | 191 |
| Pneumonia | 635 | 3 | 74 | 137 | 48 |
| Loss of consciousness | 612 | 6 | 60 | 285 | 147 |
| Headache | 610 | 6 | 92 | 251 | 90 |
| Hypertension | 583 | 4 | 131 | 350 | 190 |