Opioid Agonist [EPC]: Side Effects & Safety Data for 15 Drugs
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Opioid Agonist [EPC] includes 15 drugs with a combined 759,805 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
15
Drugs in Class
759,805
Combined Reports
All Opioid Agonist [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| OXYCODONE | Oxycodone Hydrochloride | 190,468 | 55,140 | 21,279 | 28.9% |
| MORPHINE | Morphine Sulfate | 120,595 | 38,212 | 17,386 | 31.7% |
| FENTANYL | FENTANYL | 94,485 | 42,491 | 15,153 | 45.0% |
| HYDROMORPHONE | Hydromorphone Hydrochloride | 83,446 | 28,491 | 10,395 | 34.1% |
| TRAMADOL | ConZip | 75,664 | 14,555 | 19,235 | 19.2% |
| HYDROCODONE | Hydrocodone Bitartrate | 47,828 | 24,200 | 3,569 | 50.6% |
| OXYMORPHONE | Oxymorphone Hydrochloride | 38,077 | 22,403 | 2,692 | 58.8% |
| TAPENTADOL | Nucynta | 29,208 | 20,205 | 3,304 | 69.2% |
| METHADONE | METHADONE HYDROCHLORIDE | 26,279 | 10,719 | 5,514 | 40.8% |
| CODEINE | Codeine-Guaifenesin | 21,932 | 5,971 | 3,758 | 27.2% |
| LOPERAMIDE | Anti-diarrheal | 18,011 | 1,551 | 4,298 | 8.6% |
| MEPERIDINE | MEPERIDINE HYDROCHLORIDE | 6,404 | 466 | 551 | 7.3% |
| SUFENTANIL | Sufentanil Citrate | 4,323 | 382 | 1,651 | 8.8% |
| REMIFENTANIL | Remifentanil Hydrochloride | 2,733 | 210 | 995 | 7.7% |
| LEVORPHANOL | Levorphanol Tartrate | 352 | 24 | 30 | 6.8% |
Common Side Effects in Opioid Agonist [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug dependence | 257,169 | 31,868 |
| Overdose | 176,890 | 75,896 |
| Pain | 137,512 | 7,188 |
| Death | 132,702 | 132,563 |
| Toxicity to various agents | 113,719 | 93,636 |
| Emotional distress | 110,105 | 2,591 |
| Drug withdrawal syndrome | 90,296 | 4,206 |
| Drug abuse | 58,058 | 35,871 |
| Drug ineffective | 40,492 | 4,013 |
| Dependence | 37,179 | 4,179 |