Proton Pump Inhibitors [MoA]: Side Effects & Safety Data for 6 Drugs
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Proton Pump Inhibitors [MoA] includes 6 drugs with a combined 337,788 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
6
Drugs in Class
337,788
Combined Reports
All Proton Pump Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| OMEPRAZOLE | omeprazole sodium bicarbonate | 87,111 | 8,515 | 19,847 | 9.8% |
| PANTOPRAZOLE | Pantoprazole Sodium | 78,692 | 9,456 | 23,952 | 12.0% |
| ESOMEPRAZOLE | Esomeprazole Magnesium | 75,631 | 7,030 | 15,221 | 9.3% |
| LANSOPRAZOLE | Lansoprazole | 60,931 | 6,896 | 12,277 | 11.3% |
| DEXLANSOPRAZOLE | Dexlansoprazole | 24,007 | 2,800 | 1,920 | 11.7% |
| RABEPRAZOLE | Rabeprazole Sodium | 11,416 | 1,676 | 2,143 | 14.7% |
Common Side Effects in Proton Pump Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Chronic kidney disease | 152,430 | 16,656 |
| Acute kidney injury | 80,402 | 11,449 |
| Renal failure | 63,159 | 11,784 |
| End stage renal disease | 44,939 | 9,931 |
| Renal injury | 40,038 | 3,470 |
| Tubulointerstitial nephritis | 19,585 | 2,797 |
| Drug ineffective | 17,334 | 1,211 |
| Gastrooesophageal reflux disease | 16,042 | 756 |
| Off label use | 13,194 | 1,900 |
| Pain | 12,949 | 1,132 |