Vinca Alkaloid [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Febrile neutropenia | 9,479 | 3 | 1,112 | 6,242 | 1,617 |
| Off label use | 7,714 | 3 | 1,770 | 2,325 | 710 |
| Disease progression | 6,040 | 3 | 1,436 | 794 | 167 |
| Neutropenia | 5,915 | 3 | 955 | 2,332 | 908 |
| Drug ineffective | 4,777 | 3 | 1,430 | 1,103 | 479 |
| Pyrexia | 4,015 | 3 | 541 | 2,836 | 443 |
| Product use in unapproved indication | 3,583 | 3 | 837 | 971 | 322 |
| Thrombocytopenia | 3,415 | 3 | 663 | 1,262 | 478 |
| Anaemia | 3,103 | 3 | 494 | 1,419 | 451 |
| Sepsis | 3,093 | 3 | 1,541 | 1,439 | 513 |
| Pneumonia | 2,725 | 3 | 957 | 1,538 | 447 |
| Nausea | 2,627 | 3 | 279 | 1,379 | 279 |
| Death | 2,531 | 3 | 2,531 | 297 | 63 |
| Pancytopenia | 2,454 | 3 | 604 | 1,200 | 318 |
| Vomiting | 2,291 | 3 | 319 | 1,374 | 263 |
| Malignant neoplasm progression | 2,248 | 3 | 668 | 394 | 116 |
| Neuropathy peripheral | 2,226 | 3 | 237 | 573 | 92 |
| Diarrhoea | 2,142 | 3 | 374 | 1,196 | 166 |
| Infection | 2,048 | 3 | 870 | 612 | 174 |
| Mucosal inflammation | 1,856 | 3 | 269 | 930 | 158 |
| Fatigue | 1,743 | 3 | 267 | 884 | 167 |
| Septic shock | 1,670 | 3 | 956 | 951 | 439 |
| Leukopenia | 1,618 | 3 | 301 | 551 | 192 |
| Myelosuppression | 1,466 | 3 | 136 | 699 | 201 |
| Neoplasm progression | 1,404 | 3 | 419 | 306 | 55 |
| Dyspnoea | 1,388 | 3 | 275 | 831 | 206 |
| Acute kidney injury | 1,381 | 3 | 359 | 901 | 226 |
| Abdominal pain | 1,314 | 3 | 173 | 893 | 89 |
| Respiratory failure | 1,267 | 3 | 729 | 774 | 408 |
| Toxicity to various agents | 1,262 | 3 | 500 | 290 | 122 |