Does AFLIBERCEPT Cause Intestinal perforation? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Intestinal perforation have been filed in association with AFLIBERCEPT (EYLEA). This represents 0.1% of all adverse event reports for AFLIBERCEPT.
14
Reports of Intestinal perforation with AFLIBERCEPT
0.1%
of all AFLIBERCEPT reports
8
Deaths
8
Hospitalizations
How Dangerous Is Intestinal perforation From AFLIBERCEPT?
Of the 14 reports, 8 (57.1%) resulted in death, 8 (57.1%) required hospitalization, and 1 (7.1%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for AFLIBERCEPT.
What Other Side Effects Does AFLIBERCEPT Cause?
Death (7,669)
Visual impairment (1,836)
Blindness (1,337)
Endophthalmitis (1,289)
Off label use (1,156)
Eye pain (1,057)
Product dose omission issue (1,051)
Blindness unilateral (1,012)
Vision blurred (1,012)
Visual acuity reduced (993)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which AFLIBERCEPT Alternatives Have Lower Intestinal perforation Risk?
AFLIBERCEPT vs AGALSIDASE ALFA
AFLIBERCEPT vs AGALSIDASE BETA
AFLIBERCEPT vs AGOMELATINE
AFLIBERCEPT vs ALAWAY
AFLIBERCEPT vs ALBENDAZOLE