Does CARFILZOMIB Cause Intestinal perforation? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Intestinal perforation have been filed in association with CARFILZOMIB (KYPROLIS). This represents 0.1% of all adverse event reports for CARFILZOMIB.
12
Reports of Intestinal perforation with CARFILZOMIB
0.1%
of all CARFILZOMIB reports
4
Deaths
6
Hospitalizations
How Dangerous Is Intestinal perforation From CARFILZOMIB?
Of the 12 reports, 4 (33.3%) resulted in death, 6 (50.0%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for CARFILZOMIB.
What Other Side Effects Does CARFILZOMIB Cause?
Plasma cell myeloma (2,238)
Off label use (2,120)
Death (1,442)
Thrombocytopenia (1,265)
Fatigue (1,048)
Pneumonia (1,016)
Pyrexia (969)
Anaemia (910)
Dyspnoea (881)
Neutropenia (874)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which CARFILZOMIB Alternatives Have Lower Intestinal perforation Risk?
CARFILZOMIB vs CARGLUMIC ACID
CARFILZOMIB vs CARIPRAZINE
CARFILZOMIB vs CARISOPRODOL
CARFILZOMIB vs CARMUSTINE
CARFILZOMIB vs CARTEOLOL