Does CARFILZOMIB Cause Leukoencephalopathy? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Leukoencephalopathy have been filed in association with CARFILZOMIB (KYPROLIS). This represents 0.1% of all adverse event reports for CARFILZOMIB.
13
Reports of Leukoencephalopathy with CARFILZOMIB
0.1%
of all CARFILZOMIB reports
0
Deaths
2
Hospitalizations
How Dangerous Is Leukoencephalopathy From CARFILZOMIB?
Of the 13 reports, 2 (15.4%) required hospitalization, and 1 (7.7%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for CARFILZOMIB.
What Other Side Effects Does CARFILZOMIB Cause?
Plasma cell myeloma (2,238)
Off label use (2,120)
Death (1,442)
Thrombocytopenia (1,265)
Fatigue (1,048)
Pneumonia (1,016)
Pyrexia (969)
Anaemia (910)
Dyspnoea (881)
Neutropenia (874)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which CARFILZOMIB Alternatives Have Lower Leukoencephalopathy Risk?
CARFILZOMIB vs CARGLUMIC ACID
CARFILZOMIB vs CARIPRAZINE
CARFILZOMIB vs CARISOPRODOL
CARFILZOMIB vs CARMUSTINE
CARFILZOMIB vs CARTEOLOL