Does MELPHALAN Cause Hepatotoxicity? 53 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 53 reports of Hepatotoxicity have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.3% of all adverse event reports for MELPHALAN.
53
Reports of Hepatotoxicity with MELPHALAN
0.3%
of all MELPHALAN reports
15
Deaths
14
Hospitalizations
How Dangerous Is Hepatotoxicity From MELPHALAN?
Of the 53 reports, 15 (28.3%) resulted in death, 14 (26.4%) required hospitalization, and 5 (9.4%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for MELPHALAN.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which MELPHALAN Alternatives Have Lower Hepatotoxicity Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL