METHOTREXATE for Sjogren's syndrome: Side Effects & Safety Data
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There are 237 adverse event reports in the FDA FAERS database where METHOTREXATE was used for Sjogren's syndrome.
Most Reported Side Effects for METHOTREXATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 70,142 | 27.6% | 2,652 | 9,752 |
| Rheumatoid arthritis | 29,254 | 11.5% | 2,111 | 6,669 |
| Off label use | 24,020 | 9.5% | 3,417 | 7,881 |
| Pain | 23,773 | 9.4% | 1,981 | 5,911 |
| Drug intolerance | 22,555 | 8.9% | 1,490 | 4,290 |
| Arthralgia | 21,831 | 8.6% | 1,776 | 5,744 |
| Fatigue | 19,885 | 7.8% | 2,005 | 5,458 |
| Nausea | 18,715 | 7.4% | 1,537 | 5,866 |
| Joint swelling | 17,657 | 7.0% | 1,963 | 4,442 |
| Drug hypersensitivity | 16,677 | 6.6% | 1,413 | 3,985 |
| Rash | 15,519 | 6.1% | 2,143 | 4,878 |
| Condition aggravated | 14,938 | 5.9% | 1,927 | 4,851 |
| Treatment failure | 14,672 | 5.8% | 1,172 | 2,598 |
| Alopecia | 14,360 | 5.7% | 1,673 | 3,214 |
| Abdominal discomfort | 13,237 | 5.2% | 1,784 | 3,600 |
Other Indications for METHOTREXATE
Rheumatoid arthritis (84,654)
Product used for unknown indication (56,611)
Acute lymphocytic leukaemia (11,187)
Psoriatic arthropathy (6,997)
Psoriasis (6,628)
Prophylaxis against graft versus host disease (5,226)
Diffuse large b-cell lymphoma (2,761)
Crohn's disease (2,432)
Juvenile idiopathic arthritis (2,220)
Central nervous system lymphoma (2,075)
Other Drugs Used for Sjogren's syndrome
RITUXIMAB (928)
HYDROXYCHLOROQUINE (401)
ETANERCEPT (180)
ADALIMUMAB (134)
MYCOPHENOLATE MOFETIL (130)
PREDNISONE (124)
CYCLOSPORINE (122)
PREDNISOLONE (121)
TOFACITINIB (104)
AZATHIOPRINE (97)