Does METHOTREXATE Cause Spina bifida? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Spina bifida have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
9
Reports of Spina bifida with METHOTREXATE
0.0%
of all METHOTREXATE reports
0
Deaths
3
Hospitalizations
How Dangerous Is Spina bifida From METHOTREXATE?
Of the 9 reports, 3 (33.3%) required hospitalization, and 1 (11.1%) were considered life-threatening.
Is Spina bifida Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Spina bifida?
OXYCODONE (268)
ACETAMINOPHEN\OXYCODONE (200)
ACETAMINOPHEN\HYDROCODONE (188)
HYDROMORPHONE (174)
MORPHINE (159)
LAMOTRIGINE (142)
TRAMADOL (136)
BUPRENORPHINE (107)
VALPROIC ACID (101)
HYDROCODONE (93)
Which METHOTREXATE Alternatives Have Lower Spina bifida Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA