Does METHOTREXATE Cause Stevens-johnson syndrome? 175 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 175 reports of Stevens-johnson syndrome have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
175
Reports of Stevens-johnson syndrome with METHOTREXATE
0.1%
of all METHOTREXATE reports
64
Deaths
91
Hospitalizations
How Dangerous Is Stevens-johnson syndrome From METHOTREXATE?
Of the 175 reports, 64 (36.6%) resulted in death, 91 (52.0%) required hospitalization, and 34 (19.4%) were considered life-threatening.
Is Stevens-johnson syndrome Listed in the Official Label?
Yes, Stevens-johnson syndrome is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Stevens-johnson syndrome?
LAMOTRIGINE (1,384)
ALLOPURINOL (715)
IBUPROFEN (711)
SULFAMETHOXAZOLE\TRIMETHOPRIM (665)
ACETAMINOPHEN (649)
CARBAMAZEPINE (440)
PEMBROLIZUMAB (395)
LEVETIRACETAM (374)
CIPROFLOXACIN (349)
VANCOMYCIN (313)
Which METHOTREXATE Alternatives Have Lower Stevens-johnson syndrome Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA