Does NELARABINE Cause Leukoencephalopathy? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Leukoencephalopathy have been filed in association with NELARABINE (Nelarabine). This represents 1.9% of all adverse event reports for NELARABINE.
14
Reports of Leukoencephalopathy with NELARABINE
1.9%
of all NELARABINE reports
0
Deaths
5
Hospitalizations
How Dangerous Is Leukoencephalopathy From NELARABINE?
Of the 14 reports, 5 (35.7%) required hospitalization, and 1 (7.1%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for NELARABINE.
What Other Side Effects Does NELARABINE Cause?
Febrile neutropenia (67)
Drug ineffective (50)
Myelopathy (47)
Neurotoxicity (47)
Neuropathy peripheral (45)
Muscular weakness (42)
Sepsis (39)
Peripheral sensory neuropathy (38)
Neutropenia (37)
Off label use (37)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which NELARABINE Alternatives Have Lower Leukoencephalopathy Risk?
NELARABINE vs NELFINAVIR
NELARABINE vs NELVUTAMIG
NELARABINE vs NEMOLIZUMAB
NELARABINE vs NEMOLIZUMAB-ILTO
NELARABINE vs NEOMYCIN