Does NIRAPARIB Cause Intestinal perforation? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Intestinal perforation have been filed in association with NIRAPARIB (ZEJULA). This represents 0.1% of all adverse event reports for NIRAPARIB.
10
Reports of Intestinal perforation with NIRAPARIB
0.1%
of all NIRAPARIB reports
4
Deaths
8
Hospitalizations
How Dangerous Is Intestinal perforation From NIRAPARIB?
Of the 10 reports, 4 (40.0%) resulted in death, 8 (80.0%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for NIRAPARIB.
What Other Side Effects Does NIRAPARIB Cause?
Nausea (5,794)
Fatigue (5,240)
Constipation (4,128)
Platelet count decreased (4,102)
Insomnia (2,861)
Blood pressure increased (2,464)
Headache (2,383)
Off label use (2,213)
Vomiting (2,029)
Carbohydrate antigen 125 increased (1,868)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which NIRAPARIB Alternatives Have Lower Intestinal perforation Risk?
NIRAPARIB vs NIRMATRELVIR\RITONAVIR
NIRAPARIB vs NIROGACESTAT
NIRAPARIB vs NIROGACESTAT HYDROBROMIDE
NIRAPARIB vs NIRSEVIMAB
NIRAPARIB vs NIRSEVIMAB-ALIP