Does PEGASPARGASE Cause Large intestine perforation? 13 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 13 reports of Large intestine perforation have been filed in association with PEGASPARGASE (ONCASPAR). This represents 0.1% of all adverse event reports for PEGASPARGASE.
13
Reports of Large intestine perforation with PEGASPARGASE
0.1%
of all PEGASPARGASE reports
0
Deaths
8
Hospitalizations
How Dangerous Is Large intestine perforation From PEGASPARGASE?
Of the 13 reports, 8 (61.5%) required hospitalization, and 6 (46.2%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PEGASPARGASE. However, 13 reports have been filed with the FAERS database.
What Other Side Effects Does PEGASPARGASE Cause?
Febrile neutropenia (1,589)
Pyrexia (706)
Febrile bone marrow aplasia (668)
Sepsis (548)
Vomiting (530)
Neutropenia (521)
Abdominal pain (469)
Hypertriglyceridaemia (399)
Hypotension (388)
Thrombocytopenia (382)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which PEGASPARGASE Alternatives Have Lower Large intestine perforation Risk?
PEGASPARGASE vs PEGASYS
PEGASPARGASE vs PEGCETACOPLAN
PEGASPARGASE vs PEGFILGRASTIM
PEGASPARGASE vs PEGFILGRASTIM-APGF
PEGASPARGASE vs PEGFILGRASTIM-BMEZ