Does PIPERACILLIN\TAZOBACTAM Cause Leukoencephalopathy? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Leukoencephalopathy have been filed in association with PIPERACILLIN\TAZOBACTAM. This represents 0.1% of all adverse event reports for PIPERACILLIN\TAZOBACTAM.
10
Reports of Leukoencephalopathy with PIPERACILLIN\TAZOBACTAM
0.1%
of all PIPERACILLIN\TAZOBACTAM reports
7
Deaths
3
Hospitalizations
How Dangerous Is Leukoencephalopathy From PIPERACILLIN\TAZOBACTAM?
Of the 10 reports, 7 (70.0%) resulted in death, 3 (30.0%) required hospitalization.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for PIPERACILLIN\TAZOBACTAM. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does PIPERACILLIN\TAZOBACTAM Cause?
Drug ineffective (2,273)
Off label use (1,586)
Acute kidney injury (1,539)
Drug reaction with eosinophilia and systemic symptoms (1,157)
Pyrexia (1,113)
Rash (962)
Condition aggravated (928)
Thrombocytopenia (694)
Diarrhoea (671)
Rash maculo-papular (629)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which PIPERACILLIN\TAZOBACTAM Alternatives Have Lower Leukoencephalopathy Risk?
PIPERACILLIN\TAZOBACTAM vs PIRACETAM
PIPERACILLIN\TAZOBACTAM vs PIRARUBICIN
PIPERACILLIN\TAZOBACTAM vs PIRFENIDONE
PIPERACILLIN\TAZOBACTAM vs PIRIBEDIL
PIPERACILLIN\TAZOBACTAM vs PIRITRAMIDE