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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Catechol O-Methyltransferase Inhibitors [MoA] — Common Side Effects

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Side Effect Total Reports Drugs Deaths Hosp. Life-Threat.
Dyskinesia 421 2 57 151 7
Hallucination 266 3 10 90 1
Fall 200 2 48 97 1
Parkinson's disease 179 3 14 60 2
Tremor 162 2 5 34 1
Dysphagia 150 2 7 66 4
Confusional state 150 2 38 54 1
Therapeutic response shortened 149 2 0 64 1
Gait disturbance 143 2 4 35 0
Constipation 135 2 4 31 1
Dystonia 132 2 0 54 0
Somnolence 124 2 8 29 1
Drug ineffective 122 2 7 21 0
Hallucination, visual 114 2 6 55 0
Muscle rigidity 110 2 4 44 5
Orthostatic hypotension 109 2 37 65 4
Dizziness 106 2 0 30 2
Malaise 98 2 2 17 1
Death 96 2 96 17 0
Psychotic disorder 95 2 2 67 7
Insomnia 95 2 0 16 1
Anxiety 95 2 3 30 3
Delusion 93 2 6 35 0
Balance disorder 89 2 1 14 1
Agitation 89 2 36 27 0
Off label use 88 2 29 29 0
Wrong technique in product usage process 87 2 6 30 1
Fatigue 87 2 0 21 0
On and off phenomenon 84 2 1 29 0
Feeling abnormal 81 2 2 15 5
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