Estrogen Receptor Antagonist [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Malignant neoplasm progression | 3,349 | 2 | 488 | 424 | 83 |
| Nausea | 2,964 | 2 | 239 | 742 | 102 |
| Fatigue | 2,921 | 2 | 196 | 561 | 77 |
| Death | 2,176 | 2 | 2,175 | 209 | 30 |
| Diarrhoea | 1,703 | 2 | 104 | 455 | 77 |
| Metastases to bone | 1,576 | 2 | 97 | 216 | 51 |
| Disease progression | 1,498 | 2 | 117 | 112 | 25 |
| Neutropenia | 1,492 | 2 | 141 | 315 | 99 |
| Vomiting | 1,476 | 2 | 182 | 507 | 70 |
| Metastases to liver | 1,292 | 2 | 179 | 161 | 45 |
| Drug ineffective | 1,227 | 2 | 101 | 174 | 47 |
| Pain | 1,186 | 2 | 98 | 312 | 29 |
| Breast cancer metastatic | 1,170 | 2 | 252 | 204 | 41 |
| Asthenia | 1,066 | 2 | 154 | 330 | 47 |
| Arthralgia | 1,062 | 2 | 39 | 169 | 14 |
| Decreased appetite | 1,018 | 2 | 85 | 277 | 30 |
| Dyspnoea | 984 | 2 | 141 | 428 | 47 |
| Neoplasm progression | 929 | 2 | 155 | 123 | 12 |
| Rash | 798 | 2 | 38 | 180 | 37 |
| Constipation | 798 | 2 | 39 | 161 | 17 |
| Anaemia | 757 | 2 | 146 | 301 | 61 |
| Cough | 750 | 2 | 66 | 209 | 22 |
| Headache | 748 | 2 | 51 | 186 | 27 |
| Off label use | 727 | 2 | 102 | 193 | 29 |
| Malaise | 708 | 2 | 44 | 232 | 46 |
| Dizziness | 698 | 2 | 60 | 213 | 25 |
| Breast cancer | 684 | 1 | 95 | 93 | 25 |
| White blood cell count decreased | 675 | 2 | 42 | 138 | 37 |
| Alopecia | 667 | 2 | 22 | 92 | 14 |
| Back pain | 660 | 2 | 44 | 150 | 24 |