Full Opioid Agonists [MoA]: Side Effects & Safety Data for 12 Drugs
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Full Opioid Agonists [MoA] includes 12 drugs with a combined 664,758 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
12
Drugs in Class
664,758
Combined Reports
All Full Opioid Agonists [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| OXYCODONE | Oxycodone Hydrochloride | 190,468 | 55,140 | 21,279 | 28.9% |
| MORPHINE | Morphine Sulfate | 120,595 | 38,212 | 17,386 | 31.7% |
| FENTANYL | FENTANYL | 94,485 | 42,491 | 15,153 | 45.0% |
| HYDROMORPHONE | Hydromorphone Hydrochloride | 83,446 | 28,491 | 10,395 | 34.1% |
| TRAMADOL | ConZip | 75,664 | 14,555 | 19,235 | 19.2% |
| OXYMORPHONE | Oxymorphone Hydrochloride | 38,077 | 22,403 | 2,692 | 58.8% |
| METHADONE | METHADONE HYDROCHLORIDE | 26,279 | 10,719 | 5,514 | 40.8% |
| CODEINE | Codeine-Guaifenesin | 21,932 | 5,971 | 3,758 | 27.2% |
| MEPERIDINE | MEPERIDINE HYDROCHLORIDE | 6,404 | 466 | 551 | 7.3% |
| SUFENTANIL | Sufentanil Citrate | 4,323 | 382 | 1,651 | 8.8% |
| REMIFENTANIL | Remifentanil Hydrochloride | 2,733 | 210 | 995 | 7.7% |
| LEVORPHANOL | Levorphanol Tartrate | 352 | 24 | 30 | 6.8% |
Common Side Effects in Full Opioid Agonists [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug dependence | 224,872 | 27,375 |
| Overdose | 144,628 | 56,230 |
| Pain | 120,246 | 6,373 |
| Emotional distress | 96,276 | 2,342 |
| Death | 94,298 | 94,185 |
| Toxicity to various agents | 81,798 | 67,136 |
| Drug withdrawal syndrome | 75,914 | 3,634 |
| Drug abuse | 48,318 | 30,668 |
| Drug hypersensitivity | 33,766 | 2,756 |
| Dependence | 33,414 | 3,752 |