Organic Anion Transporting Polypeptide 2B1 Inhibitors [MoA] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Diarrhoea | 864 | 2 | 30 | 138 | 5 |
| Pruritus | 238 | 2 | 3 | 20 | 1 |
| Death | 228 | 2 | 226 | 42 | 1 |
| Off label use | 204 | 2 | 6 | 55 | 1 |
| Hospitalisation | 138 | 1 | 25 | 138 | 1 |
| Inappropriate schedule of product administration | 115 | 1 | 1 | 14 | 0 |
| Drug ineffective | 98 | 2 | 2 | 11 | 0 |
| Vomiting | 82 | 2 | 1 | 20 | 0 |
| Product use issue | 78 | 2 | 2 | 29 | 0 |
| Abdominal pain | 74 | 2 | 3 | 13 | 2 |
| Nausea | 72 | 2 | 1 | 14 | 2 |
| Therapy interrupted | 64 | 2 | 2 | 27 | 2 |
| Abdominal pain upper | 61 | 2 | 0 | 10 | 0 |
| Liver transplant | 58 | 1 | 2 | 32 | 0 |
| Hepatic enzyme increased | 56 | 1 | 0 | 4 | 0 |
| Abdominal distension | 52 | 1 | 1 | 10 | 0 |
| Abdominal discomfort | 52 | 2 | 0 | 3 | 0 |
| Product use in unapproved indication | 47 | 1 | 4 | 15 | 2 |
| Dehydration | 40 | 1 | 1 | 21 | 2 |
| Constipation | 39 | 2 | 0 | 12 | 1 |
| Dizziness | 38 | 2 | 0 | 6 | 0 |
| Product dose omission issue | 37 | 2 | 0 | 4 | 1 |
| Decreased appetite | 36 | 2 | 0 | 9 | 0 |
| Blood bilirubin increased | 36 | 1 | 2 | 6 | 0 |
| Jaundice | 33 | 1 | 1 | 6 | 1 |
| Fall | 32 | 1 | 5 | 26 | 0 |
| Treatment noncompliance | 31 | 2 | 8 | 11 | 0 |
| Alanine aminotransferase increased | 30 | 1 | 1 | 2 | 0 |
| Nasopharyngitis | 29 | 1 | 0 | 1 | 0 |
| Condition aggravated | 29 | 2 | 1 | 8 | 0 |