Vascular Endothelial Growth Factor Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Death | 18,420 | 4 | 18,404 | 839 | 117 |
| Off label use | 14,717 | 3 | 3,775 | 2,050 | 249 |
| Diarrhoea | 5,307 | 3 | 1,162 | 2,106 | 216 |
| Disease progression | 5,200 | 3 | 1,879 | 784 | 127 |
| Fatigue | 4,879 | 3 | 1,384 | 1,384 | 140 |
| Hypertension | 4,823 | 3 | 571 | 1,382 | 186 |
| Nausea | 4,716 | 4 | 1,061 | 1,553 | 160 |
| Drug ineffective | 4,280 | 3 | 521 | 480 | 96 |
| Visual impairment | 3,899 | 3 | 54 | 492 | 15 |
| Vomiting | 3,388 | 3 | 820 | 1,514 | 147 |
| Anaemia | 3,383 | 3 | 608 | 1,367 | 197 |
| No adverse event | 3,136 | 3 | 11 | 4 | 3 |
| Neutropenia | 3,057 | 3 | 478 | 790 | 184 |
| Blindness | 2,944 | 3 | 31 | 325 | 17 |
| Pyrexia | 2,788 | 3 | 544 | 1,739 | 139 |
| Asthenia | 2,787 | 4 | 818 | 1,052 | 89 |
| Visual acuity reduced | 2,786 | 3 | 68 | 307 | 18 |
| Endophthalmitis | 2,734 | 3 | 26 | 427 | 4 |
| Decreased appetite | 2,684 | 4 | 694 | 1,009 | 80 |
| Proteinuria | 2,472 | 3 | 326 | 487 | 67 |
| Thrombocytopenia | 2,424 | 4 | 454 | 685 | 171 |
| Intentional product use issue | 2,413 | 3 | 404 | 425 | 38 |
| Dyspnoea | 2,355 | 3 | 631 | 1,239 | 130 |
| Headache | 2,257 | 3 | 347 | 670 | 64 |
| Vision blurred | 2,205 | 3 | 62 | 306 | 20 |
| Neuropathy peripheral | 2,155 | 3 | 330 | 427 | 55 |
| Eye pain | 2,022 | 3 | 18 | 260 | 16 |
| Pain | 1,952 | 3 | 545 | 632 | 42 |
| Abdominal pain | 1,922 | 3 | 530 | 1,080 | 76 |
| Myelosuppression | 1,750 | 2 | 48 | 599 | 113 |