METHOTREXATE for Hypertension: Side Effects & Safety Data
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There are 13 adverse event reports in the FDA FAERS database where METHOTREXATE was used for Hypertension.
Most Reported Side Effects for METHOTREXATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 70,142 | 27.6% | 2,652 | 9,752 |
| Rheumatoid arthritis | 29,254 | 11.5% | 2,111 | 6,669 |
| Off label use | 24,020 | 9.5% | 3,417 | 7,881 |
| Pain | 23,773 | 9.4% | 1,981 | 5,911 |
| Drug intolerance | 22,555 | 8.9% | 1,490 | 4,290 |
| Arthralgia | 21,831 | 8.6% | 1,776 | 5,744 |
| Fatigue | 19,885 | 7.8% | 2,005 | 5,458 |
| Nausea | 18,715 | 7.4% | 1,537 | 5,866 |
| Joint swelling | 17,657 | 7.0% | 1,963 | 4,442 |
| Drug hypersensitivity | 16,677 | 6.6% | 1,413 | 3,985 |
| Rash | 15,519 | 6.1% | 2,143 | 4,878 |
| Condition aggravated | 14,938 | 5.9% | 1,927 | 4,851 |
| Treatment failure | 14,672 | 5.8% | 1,172 | 2,598 |
| Alopecia | 14,360 | 5.7% | 1,673 | 3,214 |
| Abdominal discomfort | 13,237 | 5.2% | 1,784 | 3,600 |
Other Indications for METHOTREXATE
Rheumatoid arthritis (84,654)
Product used for unknown indication (56,611)
Acute lymphocytic leukaemia (11,187)
Psoriatic arthropathy (6,997)
Psoriasis (6,628)
Prophylaxis against graft versus host disease (5,226)
Diffuse large b-cell lymphoma (2,761)
Crohn's disease (2,432)
Juvenile idiopathic arthritis (2,220)
Central nervous system lymphoma (2,075)
Other Drugs Used for Hypertension
AMLODIPINE (20,207)
LISINOPRIL (11,824)
RAMIPRIL (10,210)
VALSARTAN (8,956)
LOSARTAN (7,966)
FUROSEMIDE (7,490)
HYDROCHLOROTHIAZIDE (7,119)
METOPROLOL (5,918)
OLMESARTAN MEDOXOMIL (5,702)
BISOPROLOL (5,520)