Does METHOTREXATE Cause Large intestine perforation? 109 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 109 reports of Large intestine perforation have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
109
Reports of Large intestine perforation with METHOTREXATE
0.0%
of all METHOTREXATE reports
33
Deaths
85
Hospitalizations
How Dangerous Is Large intestine perforation From METHOTREXATE?
Of the 109 reports, 33 (30.3%) resulted in death, 85 (78.0%) required hospitalization, and 21 (19.3%) were considered life-threatening.
Is Large intestine perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 109 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Large intestine perforation?
ADALIMUMAB (417)
BEVACIZUMAB (406)
DEXAMETHASONE (243)
PACLITAXEL (191)
CARBOPLATIN (174)
PREDNISOLONE (171)
PREDNISONE (165)
METHYLPREDNISOLONE (164)
FLUOROURACIL (162)
PEMBROLIZUMAB (157)
Which METHOTREXATE Alternatives Have Lower Large intestine perforation Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA