Does METHOTREXATE Cause Leg amputation? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Leg amputation have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
32
Reports of Leg amputation with METHOTREXATE
0.0%
of all METHOTREXATE reports
6
Deaths
17
Hospitalizations
How Dangerous Is Leg amputation From METHOTREXATE?
Of the 32 reports, 6 (18.8%) resulted in death, 17 (53.1%) required hospitalization, and 2 (6.3%) were considered life-threatening.
Is Leg amputation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Leg amputation?
CANAGLIFLOZIN (792)
INSULIN GLARGINE (157)
ADALIMUMAB (93)
METFORMIN (79)
EMPAGLIFLOZIN (67)
OXYCODONE (67)
CANAGLIFLOZIN\METFORMIN (62)
RIVAROXABAN (58)
INSULIN ASPART (49)
ETANERCEPT (43)
Which METHOTREXATE Alternatives Have Lower Leg amputation Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA