Cytoprotective Agent [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Febrile neutropenia | 1,654 | 3 | 150 | 1,155 | 166 |
| Off label use | 1,221 | 3 | 254 | 439 | 107 |
| Neutropenia | 730 | 3 | 95 | 300 | 110 |
| Pyrexia | 724 | 3 | 87 | 530 | 90 |
| Drug ineffective | 527 | 3 | 115 | 168 | 66 |
| Disease progression | 518 | 3 | 209 | 40 | 3 |
| Product use in unapproved indication | 490 | 3 | 116 | 221 | 35 |
| Vomiting | 487 | 3 | 69 | 294 | 60 |
| Nausea | 476 | 3 | 46 | 259 | 67 |
| Thrombocytopenia | 455 | 3 | 79 | 190 | 55 |
| Anaemia | 437 | 3 | 52 | 198 | 54 |
| Sepsis | 411 | 3 | 182 | 197 | 84 |
| Pancytopenia | 372 | 3 | 61 | 205 | 48 |
| Death | 337 | 3 | 337 | 39 | 8 |
| Pneumonia | 321 | 3 | 137 | 183 | 69 |
| Diarrhoea | 310 | 3 | 58 | 179 | 26 |
| Cystitis haemorrhagic | 300 | 2 | 9 | 24 | 1 |
| Respiratory failure | 290 | 3 | 190 | 181 | 101 |
| Pulmonary toxicity | 273 | 2 | 144 | 60 | 30 |
| Mucosal inflammation | 273 | 3 | 53 | 107 | 42 |
| Bacterial infection | 271 | 3 | 161 | 100 | 12 |
| Fatigue | 270 | 3 | 30 | 160 | 40 |
| Dyspnoea | 268 | 3 | 56 | 144 | 72 |
| Toxicity to various agents | 266 | 3 | 162 | 63 | 20 |
| Acute myeloid leukaemia | 265 | 3 | 141 | 75 | 41 |
| Second primary malignancy | 261 | 3 | 112 | 44 | 17 |
| Infection | 249 | 3 | 101 | 90 | 28 |
| Encephalopathy | 246 | 3 | 32 | 161 | 14 |
| Myelosuppression | 231 | 3 | 26 | 121 | 21 |
| Hypotension | 230 | 3 | 41 | 181 | 34 |